23. Answer BOTH parts of this question. The structure shown Figure Q23 represents one of the stereoisomers of a drug use
Posted: Wed Apr 27, 2022 6:36 am
23. Answer BOTH parts of this question. The structure shown Figure Q23 represents one of the stereoisomers of a drug used as a muscle relaxant in diseases where abnormal muscle activation occurs: F3C Figure Q23 (a) Reproduce the structure and indicate with a star (*) the location of the chiral centre, then use this structure to explain how the rules proposed by Cahn, Ingold and Prelog are used to prioritise the groups bonded to the chiral carbon. (5 marks) (b) Explain how this order of priority may be used to define a particular enantiomer as either Ror S. Use the structure of shown Figures Q23 to illustrate this, defining the structure shown as either Ror S. (3 marks) (c) Draw the structure of the enantiomer of this compound. (1 mark) (d) Comment on the biological activity of two enantiomers of this drug. (1 mark)