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A synthetic scheme to prepare 6 from halogenated benzoyl chloride 7 is shown below. You are not required to comment on t
Posted: Wed Apr 27, 2022 6:17 am
by answerhappygod
- A Synthetic Scheme To Prepare 6 From Halogenated Benzoyl Chloride 7 Is Shown Below You Are Not Required To Comment On T 1 (47.76 KiB) Viewed 44 times
A synthetic scheme to prepare 6 from halogenated benzoyl chloride 7 is shown below. You are not required to comment on the conversion of advanced intermediate 12 into 6. AICI voor Br Br 8 7 NH2NH2 then KOH, HOCH2CH2OH, heat Mg BrMg Br Et20 11 10 o HO HO HO OH OH HO OH 5 OH 12 e) Demonstrating the use of the CIP rules, assign R/S to the stereogenic centre of compound 8. 121 6) Propose a mechanism for the union of 7 and 8 to form 9, commenting on the regioselectivity observed in this reaction. [3] g) Propose a mechanism for the reduction of 9 to form 10. [41 h) 10 is reacted with magnesium metal to form 11 in situ. Propose a mechanism for the union of 11 and gluconolactone 5 to form 12.