Q9. Below is a schematic of a serine protease active site \& a potential substrate. Use the schematic \& the numbered at
Posted: Fri Jul 15, 2022 5:20 pm
Q9. Below is a schematic of a serine protease active site \& a potential substrate. Use the schematic \& the numbered atoms as references to answer the following 2 questions.
The serine protease would hydrolyze the bond between atoms of the substrate. Enter the numbers that correspond to the correct atoms of the substrate. To earn credit, enter the smaller number in blank1 and the larger number in blank2.
Upon binding to the substrate, atom # of the enzyme acts as a(n) (nucleophile or electrophile) \& attacks atom # on the substrate, which acts as a(n) (nucleophile or electrophile). This leads to formation of the first tetrahedral intermediate.
The serine protease would hydrolyze the bond between atoms of the substrate. Enter the numbers that correspond to the correct atoms of the substrate. To earn credit, enter the smaller number in blank1 and the larger number in blank2.
Upon binding to the substrate, atom # of the enzyme acts as a(n) (nucleophile or electrophile) \& attacks atom # on the substrate, which acts as a(n) (nucleophile or electrophile). This leads to formation of the first tetrahedral intermediate.