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Q13: Animal cells utilize rapid increases in cytosolic Ca∗+ ion concentration to respond to certain extracellular signals. This requires loeeping the cytosolic G∗∗ ion concentration very low in the absence of signal (when the cell is "at rest") and increasing the cytosolic Ca"t ion concentration when a signal is detected. Propose a mechanism by which the action of Ca+4 transport proteins in the plasma membrane can account for the reversibility of Ca+ fevels in the cytosol. Be sure to indicate whether active or passive transport is irwolved as well as the type of transport protein (channel or carrier) responsible.