Before translation, how does the eukaryotic ribosomal small subunit recognize the start codon on the mRNA? It performs a
Posted: Fri Jul 15, 2022 5:19 pm
Before translation, how does the eukaryotic ribosomal small subunit recognize the start codon on the mRNA? It performs an ATP hydrolysis within the small subunit once it encounters a Met-tRNA already bound to the AUG. It binds an Met-tRNA to the first AUG codon it encounters. It undergoes a conformational charge that recruits other proteins when it hydrogens bonds to the correct tri-nucleotide sequence. It wraps the mRNA strand to bring initiation enhancer proteins into the vicinity of the start codon. It binds an Met-tRNA to the first AUG codon AFTER the Kozak sequence.