How does the composition of TFIID allow the GTF to recognize the many different types of Pol2
Posted: Fri Jul 15, 2022 5:14 pm
What roles do the various GTF for RNA pol2 play in creating an initiation complex? - 3 pts - How does the composition of TFIID allow the GTF to recognize the many different types of Pol2 promoters? How does this complex trigger melting of the DNA? - 2 pts - What role does TFIIB play in holding the pol onto the promoter, and help the ssDNA move into the active site? - 2 pts - What important activities does TFIIH play? 3pts - At the beginning of elongation, there is a quick pause by +50, what causes this. How does the transcription machinery allow the pause to be overcome? - 3 pts - How does the HLH dimer of mad/max and myc/max impact the "pause" story? How does this change in gene expression fit into cell cycle progression - what occurs if myc is always expressed?