Molecular cell bio PLEASE EXPLAIN IN DETAIL TRUE/FALSE 1. CG islands are thought to have arisen during evolution because
Posted: Tue Jul 12, 2022 1:23 pm
Molecular cell bio
PLEASE EXPLAIN IN DETAIL
TRUE/FALSE
1. CG islands are thought to have arisen during evolutionbecause they were associated with portions of the genome thatremained unmethylated in the germ line.
2. In most differentiated tissues, daughter cells retain amemory of gene expression patterns that were present in the parentcell through mechanisms that do not involve changes in the sequenceof their genomic DNA.
3. If the site of transcript cleavage and poly-A addition for aparticular RNA in one cell is downstream of the site used forcleavage and poly-A addition for the same RNA in a second cell, theprotein produced from the longer polyadenylated RNA willnecessarily contain additional amino acids at its C-terminus.
4. In one extreme case, a single gene in Drosophila—the Dscamgene—has the potential to produce more than 38,000 differentproteins by alternative splicing; thus, the complexity of this onegene rivals the complexity of the whole human genome.
5. The gel mobility-shift assay relies on retardation of DNAunder different binding scenarios.
PLEASE EXPLAIN IN DETAIL
TRUE/FALSE
1. CG islands are thought to have arisen during evolutionbecause they were associated with portions of the genome thatremained unmethylated in the germ line.
2. In most differentiated tissues, daughter cells retain amemory of gene expression patterns that were present in the parentcell through mechanisms that do not involve changes in the sequenceof their genomic DNA.
3. If the site of transcript cleavage and poly-A addition for aparticular RNA in one cell is downstream of the site used forcleavage and poly-A addition for the same RNA in a second cell, theprotein produced from the longer polyadenylated RNA willnecessarily contain additional amino acids at its C-terminus.
4. In one extreme case, a single gene in Drosophila—the Dscamgene—has the potential to produce more than 38,000 differentproteins by alternative splicing; thus, the complexity of this onegene rivals the complexity of the whole human genome.
5. The gel mobility-shift assay relies on retardation of DNAunder different binding scenarios.