Answer Happy

In the first "Hallmarks" paper, 6 characteristics of cancer cells were enumerated. Match each one with its proper description 1. Active telomerase and stable Tissue invasion and telomeres metastasis 2. Create and maintain a capillary Evade apoptosis network Endless replicative potential 3. Do not respond to normal cell death signals Sustained angiogenesis 4. Can produce their own growth signals Self sufficiency in growth signals 5. Don't respond to normal growth suppression signals Insensitive to anti-growth signals 6. Can invade normal tissue and spread

Which of the following is most likely to produce a cell insensitive to anti-growth signals mutation of the pRB gene establishment of a capillary network amplification of the myc gene activation of telomerase