Question: The brains of patients with Alzheimer's disease show degradation of microtubule function, in part from over-ph

[answerhappygod]

Question:
The brains of patients with Alzheimer's disease show degradationof microtubule function, in partfrom over-phosphorylation of the microtubule-associated protein,tau. What might happen to neuronswhen microtubule function is disrupted? In your answer, be specificabout which structures withinneurons are likely to be affected by microtubule disruptions andhow they would be affected, and explainyour reasoning. (You should be able to answer this question in nomore than one brief paragraph.)Key points:(1) (2 points) If microtubules are disrupted, this would beexpected to affect the structure of theneuron. Since tau is limited to axons, the axon should be abnormal,but the dendrites should be normal.(2) (1 point) If axonal microtubules are damaged, this would alsointerfere with axonal transport.(3) (1 point) Without axonal transport, the synapses could not bemaintained.
My answer:
"Microtubules are basically the cytoskeleton proteins which alsopresent in the nervous system and it helps in the maintenance ofthe neurons. Neurons are composed of mainly two parts, axons anddendrites. In neurons, microtubules are the long cylindricalcytoskeleton structure over the neurons and help in the defining ofthe axons and dendrites. And the "tau" protein is also associatedwith the microtubules where phosphorylated tau protein helps in thestability maintenance of microtubules in the axons. If tau proteinis highly phosphorylated then it results in the degradation of themicrotubules. As a result axons and dendrites which were coveredwith the microtubules as the cytoskeleton, it will be lost and theaxons and dendrites will not be shaped and ultimately cause theneurodegenerative disease. As a result, patient will not be havingany regulation on the neuronal signals, there will be no signalsynapses."
Please let me know what of all 3 "key points" mentionedabove that I missed and how I might improve upon them (As thisconcept/question type may come up in class again)