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QUESTION 3 Two successive alkylations were carried out on a certain ß-ketoester M to produce compound N. In each alkylat

Posted: Tue Jul 12, 2022 1:16 pm
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Question 3 Two Successive Alkylations Were Carried Out On A Certain Ss Ketoester M To Produce Compound N In Each Alkylat 1
Question 3 Two Successive Alkylations Were Carried Out On A Certain Ss Ketoester M To Produce Compound N In Each Alkylat 1 (440.06 KiB) Viewed 46 times
QUESTION 3 Two successive alkylations were carried out on a certain ß-ketoester M to produce compound N. In each alkylation reaction the nucleophilic enolate anion was treated with an alkyl halide. Consider the following Claisen condensation reaction towards the formation of ß-ketoester M. Ester K + Ester L 1. NaOCH₂CH₂ 2. H₂O* B-keto ester M 1. Alkylation reaction I 2. Alkylation reaction II a) Draw the structures of the starting esters (K and L) and ß-ketoester M. b) Draw the alkyl halides that may be used in the synthesis of compound N. Compound N (5 marks) (1 mark) c) Compound N can further undergo hydrolysis and decarboxylation to produce a ketone. Draw the structure of the ketone. (2 marks)