QUESTION 3 Two successive alkylations were carried out on a certain ß-ketoester M to produce compound N. In each alkylat
Posted: Tue Jul 12, 2022 1:16 pm
QUESTION 3 Two successive alkylations were carried out on a certain ß-ketoester M to produce compound N. In each alkylation reaction the nucleophilic enolate anion was treated with an alkyl halide. Consider the following Claisen condensation reaction towards the formation of ß-ketoester M. Ester K + Ester L 1. NaOCH₂CH₂ 2. H₂O* B-keto ester M 1. Alkylation reaction I 2. Alkylation reaction II a) Draw the structures of the starting esters (K and L) and ß-ketoester M. b) Draw the alkyl halides that may be used in the synthesis of compound N. Compound N (5 marks) (1 mark) c) Compound N can further undergo hydrolysis and decarboxylation to produce a ketone. Draw the structure of the ketone. (2 marks)