help for rewrite make more better ti understand The analysis of EMT and its analogs were organized in two ways based on
Posted: Tue Jul 12, 2022 1:09 pm
help for rewrite make more better ti understand
The analysis of EMT and its analogs were organized in two waysbased on spectroscopic study: (a) ultra-violet visible absorptionstudy on the interactions of EMT and its analogs with Ct-DNA; (b)molar ratio Fourier transform infrared (FTIR) spectroscopic studyof EMT and its analogs with Ct-DNA. The research revealed that theinteraction between Emetine (EMT) and its analog [thioureaderivative (ETU)] with Ct-DNA showed a hypochromic effect and blueshift with k values of 1.00 x106M-1 ,4.69 x105M-1, while the second analog[dithiocarbamic acid salt derivative (EDC)] interaction with Ct-DNAshowed a hypochromic effect without any shifts witha k value of 1.28 x106M-1. This results suggests a non-covalentintercalative interaction for EMT and ETU and groove bindinginteraction for EDC via possible hydrophobic mode at studiedconcentrations.
The analysis of EMT and its analogs were organized in two waysbased on spectroscopic study: (a) ultra-violet visible absorptionstudy on the interactions of EMT and its analogs with Ct-DNA; (b)molar ratio Fourier transform infrared (FTIR) spectroscopic studyof EMT and its analogs with Ct-DNA. The research revealed that theinteraction between Emetine (EMT) and its analog [thioureaderivative (ETU)] with Ct-DNA showed a hypochromic effect and blueshift with k values of 1.00 x106M-1 ,4.69 x105M-1, while the second analog[dithiocarbamic acid salt derivative (EDC)] interaction with Ct-DNAshowed a hypochromic effect without any shifts witha k value of 1.28 x106M-1. This results suggests a non-covalentintercalative interaction for EMT and ETU and groove bindinginteraction for EDC via possible hydrophobic mode at studiedconcentrations.