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6. p53, also known as TP53 or tumor protein (EC.2.7.1.37) is a gene that codes for a protein that regulates the cell cycle and hence functions as a tumor suppressor. It is very important for cells in multicellular organisms to suppress cancer. P53 has been described as "the guardian of the genome", referring to its role in conserving stability by preventing genome mutation (Strachan and Read, 1999). The p53 protein is a phosphoprotein made of 393 amino acids Bladder cancer Lung cancer A Melanoma Now Prostate Breast Amino Acids Encoded by the mutated Human p53 Gene the progu guva sya voor Based on the information in the above table, prostate cancer is probably the result of which kind of mutation? (Empty boxes in the table are the missing amino acids in the chain) A) analog B) frameshift C) missense D) nonsense 7. It is fairly standard for antibiotic resistance to emerge in bacteria within 3 years of antibiotics being released to the market. Rapid and widespread resistance is largely due to conjugation Compounds that can inhibit conjugation may represent a way to inhibit or at least slow the progression of antibiotic resistance and the emergence of a new pathogen. What do you think may be a good target to prevent conjugation?
8. Science News Article To tackle the new coronavirus, scientists are accelerating the vaccine process. References: SAEY, T. H. (2020). Vaccine scientists target coronavirus. Science News, 197(5). 6-7. http://search.ebscohost.com/login.aspx? ... AN=1419761 51&site chost-live&custid-s3740306 Read the article included in the link to answer the following questions 1. The genetic material in all organisms is DNA. However, viruses are the exception to this rule. The genetic material in the case of MERS and SARS is 2. Why it was important for Inovio to start the research for this new virus, why the vaccine developed for MERS would not be helpful in this case? 3. What is the new approach mentioned in the article, used by the companies to develop a vaccine? 4. The above procedure used by the companies falls under which field of Genetics? 6
5. In the regular process of gene expression DNA is transcribed into mRNA through the process of transcription. Then mRNA through the process of translation produces proteins. But in the process of making the vaccine scientist are converting the virus's RNA to DNA. What do you think this process is called? Can you think of an example, where this process is being currently used for SARS CoV-2 testing? 6. NIAID and Moderna are building the Novel vaccine using mRNA, explain the concept used in the development of this type of vaccine. 7. How are molecular clamp vaccines designed to work in the case of SARS COV-2?