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Restate the answers to these at a 6th grade level and make them more concise 1. What is the difference between sickle cell blood cells and normal blood cells? - The difference between sickle cell blood cells and normal blood cells is that red blood cells have a hemoglobin, which is a protein that carries oxygen. Normal blood cells are able to move around through small blood vessels to distribute oxygen to all the body. Sickle cell blood cells have an abnormal hemoglobin. It makes the cells hard and sticky; they die early. They also get stuck and clog blood flow. 2. What is the difference between sickle- cell hemoglobin and normal hemoglobin? - The difference between sickle cell hemoglobin and normal hemoglobin is that the normal hemoglobin has glutamate at position 6 on the surface of the beta chain. The sickle hemoglobin has a valine that replaces the glutamate. A normal hemoglobin has the ability to give red blood cells a healthier path. 3. What is the difference between sickle-cell amino acid sequence and normal amino acid sequence? - The difference between sickle-cell amino acid sequence and normal amino acid sequence is that a sickle-cell amino acid sequence has glutamic acid in the sixth position, when a normal amino acid sequence has valine. 4. What is the difference between sickle-cell DNA sequence and normal DNA sequence? - The main difference between a sickle-cell DNA sequence and a normal DNA sequence is th <>
hemoglobin has glutamate at position 6 on the surface of the beta chain. The sickle hemoglobin has a valine that replaces the glutamate. A normal hemoglobin has the ability to give red blood cells a healthier path. 3. What is the difference between sickle-cell amino acid sequence and normal amino acid sequence? - The difference between sickle-cell amino acid sequence and normal amino acid sequence is that a sickle-cell amino acid sequence has glutamic acid in the sixth position, when a normal amino acid sequence has valine. 4. What is the difference between sickle-cell DNA sequence and normal DNA sequence? - The main difference between a sickle-cell DNA sequence and a normal DNA sequence is the replacement of the glutamate with valine. 5. Use all of this to explain in your own words what a mutation is and how it can cause genetic disease. - A mutation occurs when there is a change in a DNA sequence. As we live longer, our DNA sequence can change. If there is abnormal change to our sequence, it can cause a genetic disease. For example, a sickle cell hemoglobin can disrupt our DNA sequence. It makes our normal blood cells become abnormal, sticky, and rigid. A mutation can change lives; for example, cancer is caused through changes of our genes