(d) Penicillin G is easily hydrolysed in the stomach to form Compound A (see Figure Q15d). Pho- (i) Explain how this tra
Posted: Mon Jul 11, 2022 2:04 pm
Question 15 continued overleaf...
(d) Penicillin G is easily hydrolysed in the stomach to form Compound A (see Figure Q15d). Pho- (i) Explain how this transformation occurs with the use of curly arrows and written mechanistic rationale (where appropriate). (8 marks) N ww S CO₂H Penicillin G Ph H I tan HN S CO₂H Compound A Figure Q15d (ii) How does Penicillin G's sensitivity to acid affect the preferred dosing regimen for the drug? (2 marks)