Based solely on the data provided below, do you think that a 200 mg dose provides adequate unbound drug concentrations i
Posted: Mon Jul 11, 2022 1:53 pm
Based solely on the data provided below, do you think that a 200mg dose provides adequate unbound drug concentrations in theplasma?
pka = 9.9 200 mg, twice daily, Cmax 8.4 mg/L PPB = 98.8%, Solubility 0.0381 mg/mL MW = 472.6 Log P = 4.8
pka = 9.9 200 mg, twice daily, Cmax 8.4 mg/L PPB = 98.8%, Solubility 0.0381 mg/mL MW = 472.6 Log P = 4.8