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QUESTION 7. Consider the following reaction. What is the role of LDA? CHOOyEt 1.LDA, THE 2.CH₂CH₂Br LDA acts as an acid
Posted: Sun Jul 10, 2022 4:17 pm
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- Question 7 Consider The Following Reaction What Is The Role Of Lda Chooyet 1 Lda The 2 Ch Ch Br Lda Acts As An Acid 1 (20.97 KiB) Viewed 31 times
QUESTION 7. Consider the following reaction. What is the role of LDA? CHOOyEt 1.LDA, THE 2.CH₂CH₂Br LDA acts as an acid to protonate the carbonyl carbon to form a good electrophile. LDA acts as an electrophile and adds to the alkyl halide so it is easier to substitute. LDA acts as a base and removes a proton from the alpha carbon to form the enolate. LDA acts as a nucleophile and is substituted by the THF. CH₂CH3 CHCO₂Et