Answer Happy

In your adventures in the jungle you come across a jungle fowl that secretes a lysozyme which differs from the one we studied in class at two residues only: W62 and W63 have both been mutated to N. Your partner says, "These mutations won't affect the keat or KM of the enzyme." Briefly explain their reasoning. Address the lack of effect on the keat and KM separately.
In your adventures in the jungle you come across a jungle fowl that secretes a lysozyme which differs from the one we studied in class at two residues only: W62 and W63 have both been mutated to N. Your partner says, "These mutations won't affect the keat or KM of the enzyme." You respond, "You're right, but they will still affect lysozyme's activity." How will these mutations affect lysozyme's activity? Briefly justify your answer.