11. You isolate a peptide with the sequence Met-Val-Arg-Gln-Leu-Tyr-Lys-Trp a. Assuming this forms a helix, draw the hel
Posted: Thu Jul 07, 2022 12:49 pm
11. You isolate a peptide with the sequence Met-Val-Arg-Gln-Leu-Tyr-Lys-Trp a. Assuming this forms a helix, draw the helix and indicate the direction of the side chains (don't worry about getting ~3.6 AA per turn exactly, you can use any representation of a helix that we have talked about in class). b. Predict whether the mutations below will stabilize, destabilize, or not affect the helical tendency of your peptide. In one sentence for each mutation, briefly explain why. (2 points) i M1A ii. K7R c. Assuming that this peptide forms a beta strand, Draw the strand as a ribbon and indicate the direction of each of the side chains. If this was found on the surface of the protein, highlight the amino acids that would be facing the inside of the protein.