You and Ed review the protocol for generating a knockout mouse. Ed argues that the protocol will not allow you to study
Posted: Thu Jul 07, 2022 12:44 pm
You and Ed review the protocol for generating a knockout mouse. Ed argues that the protocol will not allow you to study the role of Gene X in the trophoblast. His argument is that gene targeting occurs in stem cells derived from the inner cell mass, not trophoblast cells, and concludes that the trophoblast will not include the mutated gene.Would you use the chimeras you generated directly for your experiments?
You and Ed review the protocol for generating a knockout mouse. Ed argues that the protocol will not allow you to study the role of Gene X in the trophoblast. His argument is that gene targeting occurs in stem cells derived from the inner cell mass, not trophoblast cells, and concludes that the trophoblast will not include the mutated gene.
Would you use the chimeras you generated directly for your experiments?
You and Ed review the protocol for generating a knockout mouse. Ed argues that the protocol will not allow you to study the role of Gene X in the trophoblast. His argument is that gene targeting occurs in stem cells derived from the inner cell mass, not trophoblast cells, and concludes that the trophoblast will not include the mutated gene.
Would you use the chimeras you generated directly for your experiments?