Using the pk, table, estimate pką values for the most acidic group on the compounds below, and draw the structure of the
Posted: Thu Jul 07, 2022 12:12 pm
Using the pk, table, estimate pką values for the most acidic group on the compounds below, and draw the structure of the conjugate base that results when this group donates a proton. Use the pka table above and/or from the Reference Tables. a) d. Carboxylic acid, pka ~ 5 e. Carboxylic acid, pka ~ 5 b) H OH O -NH3 -NH₂ Answer a. The most acidic group is the protonated amine, pka ~ 5-9 b. Alpha proton by the C=O group, pka ~ 18-20 c. Thiol, pka ~ 10 d) OH O H₂N SH NH₂ OH asparagine lysergic acid OH CH3