Answer Happy

Study.com Name: Investigation: Migraine Headache Relief A medical study investigated the effectiveness of a drug called Sumatriptan for treating migraine headaches among children. In this study, the researchers observed 30 children in a convenience sample who had migraine headaches. The first time they had a migraine headache, the children were given Sumatripton. The next time they were given a placebo. MATH 1150 ePortfolio Assignment Do children experience more migraine headache relief from Sumatriptan or the placebo? Of the 30 children in the study, 22 had more pain relief with Sumatriptan and 8 had more pain relief with the placebo. Step 1: Ask a research question. What is your research question? Step 2: Design a study and collect data. Identify the observational units, describe the sampling technique (Is it unbiased? Do you feel comfortable generalizing your conclusions to all people in a situation like this?) and identify the variable that is being measured/recorded on each observational unit. Describe the parameter of interest in words. (Use the symbol i to represent this parameter). State the null and alternative hypotheses 73.2% to be tested. (223) 30 Ho:p=7333 Haip L. .7333 Research question: Is Sumatripin a more effective Pain reliever then the plato for Children Observational units: Childre Sampling technique: Don probability (conveniences) meds. Variable: migraine headaches, pain relief Parameter of interest: # of children who experime pain relief from Sumatripan Null hypothesis: Alternate hypothesis: ¹ Hamalainen, M. L., Hoppu, K., & Santavuori, P. (1997). Sumatriptan for migraine attacks in children: A randomized placebo-controlled study do children with migraine respond to oral Sumatriptan differently from adults? Neurology 48 (4) 1100-1103.
Step 3: Explore the data. What is the proportion of children who experienced more pain relief with Sumatriptan? Is this more than you would expect if Sumatriptan was equally as effective as the placebo? Is it possible that we could observe 22 children from a group of 30 if all the children were just randomly selecting? Step 4: Draw inferences. Identify the statistic that summarizes the data collected in the study. Use the One Proportion applet to simulate 1000 repetitions of a random process, assuming children pick randomly/equally among the two migraine headache treatments. Report what values you input into the applet. Provide a screenshot or visualization of the output. Describe the nce model-where is the center of the simulated. distribution? Determine the approximate p-value from your simulation analysis. Interpret what this p-value represents (The p value represents the probability that....) Step 5: Formulate conclusions. Step back and think about the scope of our inference. What are the wider implications? Do you think that your conclusion holds true for people in general? What is the broader population we can generalize to? Link this back to the technique we used to gather data to answer these questions. Step 6: Look back and ahead. Summarize your findings. What would you make the researchers do differently? Why? 22 = .7333 Statistic: 30 children Inputs: Output: Description: P-value: Implications: Generalization: yes yes. The manufacturers of Sumatriptan has requested the U.S. Food and Drug Administration (FDA), a federal governing body charged with "ensuring the safety, efficacy, and security of human and veterinary drugs," to allow their drug to be marketed in the U.S. The FDA has asked you to be a U.S. Food and Drug Administration. (2018, March 28). What we do. https://www.fda.gov/about-fda/what-we-do
panelist on an advisory committee to determine whether Sumatriptan should be marketed as effective for relieving children's migraine headaches before they make a final decision to approve or reject the manufacturer's request. Provide a summary report to the FDA by completing the following items: 1. Write a paragraph summarizing your statistical analysis. Be sure to provide the relevant numerical values from your analysis and their meanings. 2. Write a paragraph describing your decision to approve or reject the manufacturer's request. Be sure to provide a justification for your decision by including information from your analysis and the study that led to your decision. Your summary report to the FDA must be professional, so be as precise as possible with your descriptions and justification.