simvastatin is an anticholesterol medication that helps to suppress LDL production. which of the following may increase
Posted: Wed Jul 06, 2022 10:23 am
simvastatin is an anticholesterol medication that helps to suppress LDL production. which of the following may increase risk of myopathy by 2.5 fold when a standard dose of 40mg is given. 1. SLCO1B1*5 the variant that encodes the organic anion transporting polypeptide 1B1, 2. UGT2B7 the variant that encodes uridine 5'diphosphoglucuronosly transferase 2B7, 3. TPMT*3A the variant that encodes thiopurine S-methyltransferase *31, 4. UGT1A1 the variant that encodes uridine 5'diphosphoglucuronosyl transferase 1A1