A 44-year-old woman comes to the physician for a follow-up examination after two separate Pap smears showed atypical squ
Posted: Mon Apr 11, 2022 7:54 am
A 44-year-old woman comes to the physician for a follow-up examination after two separate Pap smears showed atypical squamous cells of undetermined significance. Results of a molecular diagnostic test show the presence of the viral E6 protein of human papillomavirus. This protein is known to promote cell growth and malignancy by causing cellular p53 protein degradation. This degradation most likely begins when the p53 protein is targeted to which of the following types of cellular enzymes?
A. Lysine acetyltransferase
B. Lysosomal protease
C. Serine protease
D. Tyrosine kinase
E. Ubiquitin ligase
A. Lysine acetyltransferase
B. Lysosomal protease
C. Serine protease
D. Tyrosine kinase
E. Ubiquitin ligase