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7. The Opioid Crisis brought to light the common misconception that substance use disorder (SUD) cannot occur in the setting of typical drug prescribing. What are three integral components of SUD? Using opioids as an example, briefly describe how these components can manifest in the typical prescriber-patient setting. (6 marks) What are two risk factors that may contribute to an individual developing a SUD? (4 marks)
2. The inhalation of aerosolized nicotine concentrate, also called vaping, has emerged as a common method of nicotine use in recent years. Most scientific research to date has investigated the impact of nicotine on human health in smokers of tobacco cigarettes, and the long-term effects of vaping remain understudied. a. Briefly describe the pharmacokinetics of inhaled nicotine. Would you expect pharmacokinetics of nicotine delivered by vaping to be different than nicotine delivered by smoking tobacco cigarettes? (5 marks) b. How do you predict the long-term health effects of chronic vaping would compare to those of smoking? (5 marks)