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B Red blood cells are flattened biconcave discs that lack nuclei and most organelles. Most of their cytoplasm is filled with the protein hemoglobin, which transports oxygen and carbon dioxide. Examine red blood cells more closely under high magnification. They are uniquely shaped as biconcave discs with a relatively thin central region and thick peripheral region. Many resemble doughnuts or Life Saver candies because the thin central region stains more lightly than the thick peripheral region Notice that mature RBCs lack nuclei. Blood smear Colorized SEMx6400 MAKING CONNECTIONS Hemoglobin is composed of four globular protein subunits. Each subunit contains a heme pigment molecule (see figure at right). The vast majority of oxygen that is transported in the blood is bound to iron in the heme molecules. Given that another gas, carbon monoxide, has a much stronger affinity than oxygen to the same binding sites on iron, describe how carbon monoxide poisoning would occur. LM 710 72-84 um B Identify white blood cells in your field of view Most WBCs are much larger than RBCs. They contain distinct nuclei that usually stain a deep blue or purple. White blood cells play essential roles in defending the body against infection 045-1,16 um 1 231-2.85 um Red blood cells Identify platelets, which are cytoplasmic fragments derived from cells called megakaryocytes Platelets have a critical role in blood clotting and the repair of damaged blood vessels. CHCH Hemoglobin Heme antispa Sheten as: PAL>Histology > Cardiovascular System > Blood photos 361