DNA and the Central Dogma
Name (Last, First): DNA An RNA Polymerase attaches to the DNA and transcribes the DNA to mRNA Ribosome BIO 340 Activity # 1: DNA and the Central Dogma Complete: DNA Coding 5' ATG TGG ATT CTC AAG ATA AAT TCT 3' DNA template 3' 5' Cytoplasm Nucleus Nuclear pore mRNA H.H Use the mRNA codon sequence and the genetic code table in order to find the amino acid (AA) sequence of the protein. Example: if mRNA sequence is GUU then the corresponding amino acid 3-letter is Valine (Val) and the corresponding amino acid 1-letter is V. mRNA codon 5' tRNA anti-codon 3' AA 3-letter AA 1-letter Amino acid FIRST (5') LETTER U THE GENETIC CODE ( Þ tRNA 5 UUU) UUC) UUA) UUG) CUU CUC U Phe (F) CUA CUG/ New being built types of (circle the correct one): Primary structure Tertiary structure Leu (L) Leu (L) Met (M) (initiator) AA = Amino acid Use numbers 1 to 3 to indicate the correct order of the flow of biological information. Translation Replication Transcription Š The hydroxyl group in the DNA is located on the (circle one): 5' end Amino-end (V) The alpha helix and the beta strand in a protein are SECOND LETTER A с AUU ACU AUC lle (1) ACC AUA ACA AUG ACG GUU GUC GUA GUG Created by Dr. Susan A. Holechek for BIO 340 (2022). Illustration by James Direen. UCU UCC UAU) UAC) Ser UCA (S) UAA Ochre UCG UAG Amber ccu CAU CCC CAC Pro CCA (P) CAA CCG CAG AAU AAC Thr (T) GCU GAU) GCC GAC Ala GCA (A) GAA) GCG GAG) G UGU) Tyr (Y) GUCys (C) UGC) AAA AAG) (terminator) 3' end Carboxyl-end (terminator) His (H) Gin (Q) Asn (N) Secondary structure Quaternary structure Lys (K) Asp (D) Gu (E) UGA Opal terminator UGG TIp (W) CGU CGC CGA CGG/ AGU AGC) AGA) AGG GGU GGC GGA GGG Arg (R) Ser (S) Arg (R) Gly (G) U SCAG с А UCACUCAG U 24 DC с 3' G in THIRD (3) LETTER
DNA and the Central Dogma
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