Answer Happy

Case 1: Due to the outbreak of Dengue fever, Sam is struggling to have the vaccine for the Dengue virus. After the market search, he noticed there are three brands of Dengue vaccines available. Brand A: Generated by introduction of a 30-nucleotide deletion (termed A30) into the 3' UTR (untranslated region) of the DENV-1 genome. This DENV-1 vaccine candidate was shown to be attenuated and immunogenic. Brand B: Composed of the recombinant envelope (E) protein of the DENV-2 virus. Brand C: Dengue tetravalent vaccines (live, attenuated, including all DENV serotypes, DENV-1 to -4). Before taking the vaccine, Sam seeks advice from you. He told you he has no drug allergy history but is having corticosteroid to treat his Eczema.
Q1. Which brand of the Dengue vaccine is most suitable for Sam at this moment? A. Brand A B. Brand B C. Brand C D. All of the above Q2. Do you recommend he takes the Dengue vaccine if he is not exposed to this virus before? A. Yes B. No Q3. What happens if Sam takes the Brand A vaccine and gets an infection with DENV-2 later? A. Develop a much quicker and stronger immune response to prevent DENV-2 infection. B. Sam is still being infected with DENV-2 but the clinical manifestations are highly reduced. C. Develop much more severe symptoms and result in hemorrhagic fever. D. Sam becomes an asymptomatic carrier and can spread the virus in society. Q4. If you need to go to the endemic area with Dengue infection, which vaccine do you prefer to have before your travel? A. Brand A B. Brand B C. Brand C D. All of the above Q5. Which of the above vaccine needs to be injected together with the adjuvant? A. Brand A B. Brand B C. Brand C D. All of the above