A female patient (35 years old, 65 kg), normal renal function will receive an antibiotic (t1/2 = 7h, V = 23% BW) by IV i
Posted: Tue Mar 15, 2022 3:09 pm
A female patient (35 years old, 65 kg), normal renal function
will receive an antibiotic (t1/2 = 7h, V = 23% BW) by IV
infusion. A therapeutic concentration (Cpss) of 10 µg/mL is
desired. If the total body clearance declined 50% due to partial
renal failure, what new infusion rate would you recommend to
maintain the desired steady-state plasma level of 10 mcg/mL?
will receive an antibiotic (t1/2 = 7h, V = 23% BW) by IV
infusion. A therapeutic concentration (Cpss) of 10 µg/mL is
desired. If the total body clearance declined 50% due to partial
renal failure, what new infusion rate would you recommend to
maintain the desired steady-state plasma level of 10 mcg/mL?