Answer Happy

1. Employs the three doses two species criterion
Acute toxicity
Chronic toxicity
Carcinogenic Potential
Mutagenic Potential
Subacute Toxicity
2. Determines the maximum tolerated dose
Acute toxicity
Chronic toxicity
Carcinogenic Potential
Mutagenic Potential
Subacute Toxicity
3. A full agonist produces less than the full effect, even
when it has saturated the receptors. An inverse agonist is a drug
that binds to the inactive state of receptor molecules and
decreases constitutive activity.
Only the FIRST statement is
CORRECT.
Only the SECOND statement is
CORRECT.
BOTH statements are
CORRECT.
BOTH statements are
INCORRECT.
4. The receptor site is a specific binding region of the
macromolecule. The receptor site has high and selective affinity to
the drug molecule.
Only the FIRST statement is
CORRECT.
Only the SECOND statement is
CORRECT.
BOTH statements are
CORRECT.
BOTH statements are
INCORRECT
5. A very safe drug might be expected to have a very large
toxic dose and a much smaller effective dose. Hence, ED50 is
directly proportional to drug safety.
Only the FIRST statement is
CORRECT.
Only the SECOND statement is
CORRECT.
BOTH statements are
CORRECT.
BOTH statements are
INCORRECT.