Section B - 30 Marks answer ONLY FOUR out of the five questions. Where more than four questions are Five questions are g
Posted: Fri Mar 04, 2022 10:30 am
questions. Where more than four questions are Five questions are given. All questions carry equal marks. Students are required to answered in Section A only the first FOUR will receive credit where earned and subsequent questions will be marked 0 marks. (i) Shown below is the chemical structure of the clinically used drug A. The drug can potentially form several hydrogen bonds to water molecules. HO A O Clearly illustrate these hydrogen bonds to water using the structure of drug A below, showing the drug and water valence electron lonÄ™ pairs involved in the H-bonding process. Drug A has poor aqueous solubility. Suggest one way to increase the water solubility of the drug. Illustrate your answer with suitable chemical structure(s). [7.5 marks]
Section B - 30 Marks answer ONLY FOUR out of the five