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a) Consider the following Robinson annulation reaction. Ketone H OH Michael addition product Enone OH CH30 i) Draw the s
Posted: Thu Feb 17, 2022 11:13 am
by answerhappygod
- A Consider The Following Robinson Annulation Reaction Ketone H Oh Michael Addition Product Enone Oh Ch30 I Draw The S 1 (38.77 KiB) Viewed 68 times
a) Consider the following Robinson annulation reaction. Ketone H OH Michael addition product Enone OH CH30 i) Draw the structure of ketone H. (2 marks) ii) Write the stepwise mechanism between ketone H and enone to produce Michael addition product (8 marks) b) The carboxylic acid product below is synthesized from malonic ester. This synthesis involves four steps. Base required for the first alkylation step is NaOCHg. Malonic Ester OH 1) Draw the structure of malonic ester. (2 marks) H) Propose the appropriate alkyl halides required for the above synthesis. (2 marks) ii) Suggest the base needed for the second alkylation. (1 mark)