Case Studies/Team based discussion on Adrenergic Drums Cose 1 MR is a 26-year-old man who weighs 190 Kg. He has sought c
Posted: Thu Feb 17, 2022 11:12 am
Case Studies/Team based discussion on Adrenergic Drums Cose 1 MR is a 26-year-old man who weighs 190 Kg. He has sought counseling for weight loss, but modifications of diet and exercise alone have never really been successful for him. He recently watched a 20/20 program (aired 2/3/95) that described the use of prescription drugs as part of a weight loss program The drug therapy used a combination of fenfuramine (figure 1) and phentermine (figure 2) CH3 RO CH3 CH2C-NH2. HCI CH3 CH3 CF3 Pyutenfrie Figure 2 Phentermine 1. Explain the mechanism of action of EACH drug (including a brief structure-activity relationship).
a 2. Would the addition of a B-hydroxyl group to either of these drugs improve CNS penetration? Why, or why not?
a 2. Would the addition of a B-hydroxyl group to either of these drugs improve CNS penetration? Why, or why not?