A 41-year-old man with a history of intravenous drug use is brought to the emergency department by his roommate 20 minut

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A 41-year-old man with a history of intravenous drug use is
brought to the emergency department by his roommate 20 minutes
after he could not be aroused. The friend reports that the patient
injected himself with a drug approximately 9 hours ago. Laboratory
studies show a serum drug concentration of 0.3 mg/L. Assuming the
drug exhibits first-order, one-compartment kinetics, has a
half-life of 3 hours, and a volume of distribution of 100 L in this
patient, which of the following is the most likely approximate
quantity of the drug (in mg) injected?
A. 240
B. 480
C. 600
D. 1000
E. 1250