The degasser is broken on your HPLC but your boss wants you to proceed with your impurity assay of a finished product be
Posted: Sun Feb 13, 2022 7:59 am
questions you need to review the Mobile Phase Preparation Slide Deck.
The degasser is broken on your HPLC but your boss wants you to proceed with your impurity assay of a finished product because he wants to release the batch of material. You are using an in-house method with tight retention time criteria and a combination of UV/Vis AND Fluorescence for detection. . Do you agree that you should proceed? Why or why not? If not, what are the chromatographic impacts? To answer these