Answer Happy

and non-homologous end-joining. 5. Which statement is not correct? a) Apurinic/apyrimidinic (AP) endonuclease recognises and cleaves abasic sites. b) DNA glycosylase generates abasic sites upon identification of aberrant structure of DNA bases. c) Mismatch repair defects cause microsatellite instability, d) Nucleotide excision repair is defective in xeroderma pigmentosum. e) Mismatch repair defects are implicated in chromosomal translocations. 6. The DNA damage-dependent signalling involves proteins known as Adaptors, or alternatively. Media Which statement below best describes their function? a) They interact with proteins that bind directly to damaged DNA b) They direct ATM or ATR to faciliates phosphorylation of specific targets c) They interact with the 9-1-1 complex d) They mediate cell cycle arrest e) They bind directly to ATM or ATR