1 2pg 0.8 0.6 0.4 0.2 0 0.3 0.4 0.5 0.6 0.7 0.8 0.9 1 p-0 0.1 0.2 q-1 0.9 0.8 0.7 0.6 0.5 0.4 0.3 0.2 0.1 0 aa 2 - q² Aa
Posted: Thu Jun 09, 2022 2:02 pm
BIO 340 Activity # 5: Hardy-Weinberg and Chi-square analysis (PAGE 1 of 2) Name (Last, First): The following data was obtained from a previous BIO 340 class. Data obtained from reference papers regarding the USA population are also provided and will be used to determine the "Expected" frequency and counts. You will have to analyze the data and provide phenotype, genotype and allele frequencies as well as perform a chi-square analysis. Complete every single empty square. For frequencies, (O-E)²/E and X² round to two decimal places. For counts use whole numbers. Test paper S = Sodium benzoate: Hint: Find q first Allele frequency TASTERS (p² + 2pq) NON-TASTERS (q²) # Frequency # Frequency Р q BIO 340 140 60 USA N.A. 0.25 N.A. 0.75 SS (p²) ss (q²) Total Observed BIO 340 Counts Observed BIO 340 Frequency 1 Expected Frequency 0.75 Expected Counts (O-E)²/E Test paper T = Phenyilthiocarbamide (PTC) TASTERS (p² + 2pq) # Frequency BIO 340 160 USA N.A. 0.70 Observed BIO 340 Counts Observed BIO 340 Frequency Expected Frequency Expected Counts (O-E)²/E Ss (2pq) NON-TASTERS (q²) # Frequency 40 N.A. 0.30 TT (p²) Tt (2pq) 1 x² = Hint: Find q first Allele frequency Р q tt (q²) Total 1 0.30 1 x² =
BIO 340 Activity # 5: Hardy-Weinberg and Chi-square analysis (PAGE 2 of 2) Name (Last, First):_ Test paper U = Thiourea: Hint: Find q first Allele frequency TASTERS (p² + 2pq) NON-TASTERS (q²) # Frequency # Frequency Р q BIO 340 162 38 USA N.A. N.A. 0.45 0.55 UU (p²) Uu (2pq) uu (q²) Observed BIO 340 Counts Observed BIO 340 Frequency Expected Frequency Expected Counts (O-E)²/E x² = Use the Chi-square stable, which can be found in the Chi-Square Analysis of Mendel's Data page of your online textbook as well as in the Module IV Chi-square analysis lecture, in order to determine if the null hypothesis (Ho) for each of the compounds is rejected or not. Write down your answer next to each of the compounds. Sodium benzoate H₁- Phenyilthiocarbamide (PTC) Ho Thiourea Ho How do the BIO 340 results compare to those of previously published data from the USA population? Note: Compare the genotype/allele frequencies of each of the test papers. Did you expect these results? Explain why. Mention 3 reasons why most populations are NOT in Hardy-Weinberg equilibrium: 1. 2. 3 Total 1 1