A 55-year-old woman presented to her doctor with a 6-month history of burning epigastric abdominal pain. Her pain was si
Posted: Thu Jun 09, 2022 1:36 pm
A 55-year-old woman presented to her doctor with a 6-month history of burning epigastric abdominal pain. Her pain was significant and she was frequently nauseous and had vomited several times. She had admitted that she took over the counter antacids for the symptoms and that they seemed to reduce the pain and nausea. She indicated that she used over-the-counter analgesics including acetaminophen and aspirin as well as caffeine tablets. A urea breath test (UBT) was positive. An esophagogastroduodenoscopy (EGD) showed an antral ulcer. A rectal examination revealed Hemoccult-negative stool. Her mother died from gastric cancer at age 87. On examination, the patient's abdomen was soft but not distended. She had tenderness present over the stomach region. Her hematocrit was 39.3% (normal) and her basic blood biochemistry and blood counts were within normal limits. What is the most likely diagnosis for the patient (1 mark)? Describe the likely changes in the patient's gut mucosa that have led to the symptoms and the clinical findings (5 marks). What treatments and management approaches would you recommend (4 marks)? (Answers must be in written sentence form. No bullet points are allowed. Maximum words = 200. Your