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42 of 50 ■ Unsure 51241 Clear my choice Mark Defects in enzymes can have serious metabolic consequences. The table below shows the profile of four different patients presenting with metabolite levels that differ from normal expected ranges. PATIENT PROFILE W PATIENT PROFILE X Increased ATP synthesis. PATIENT PROFILE Y Decreased lactate. Elevated ammonia. PATIENT PROFILE Z Increased fatty acyl- CoA in mitochondria. Observed metabolic changes Decreased glycolysis. Decreased Decreased oxidation of Increased liver fatty acids. glutamate. oxaloacetate levels. An investigation revealed one patient harboured mutations in the enzymes arginase and carnitine acyltransferase 2, negatively affecting each enzyme's function. Which patient can this be attributed to? Select one: a. patient W b. patient Y c. patient X O d. patient Z + Report question issue Notes
47 of 50 Unsure 1 A student is attempting to summarise the differences Mark between fatty acid synthesis and fatty acid oxidation. Which option provides two statements that accurately compare an aspect of fatty acid synthesis and oxidation. Option Fatty acid synthesis 1 Uses the electron acceptor NADPH Fatty acid oxidation Uses the electron donor NADH Occurs in the cytosol 2 Occurs in the mitochondria 3 Is activated by high ATP levels in the cell Is inactivated by high ATP levels in the cell 4 Involves the addition of acetyl groups Involves the removal of acetyl groups Select one: Report question issue a. option 3 b. option 4 c. option 2 d. option 1 430 Notes (+