Answer Happy

Background:
In the kidney the malate:aspatate shuttle is the only system
that transports the electrons (reducing equivalents) held on by
cytosolic NADH into the mitochondria. The compound n-butylmalonate
completely inhibits the malate:aspartate shuttle. In an experiment
n-butylmalonate is added to an aerobic suspension of kidney cells
that are using glucose as their sole source of fuel.
Predict the effect of the inhibitor on the following and
provide a brief explanation:
i) Lactate formation
ii) Oxygen consumption by the cells
iii) The total amount of ATP produced for each glucose
molecule
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