Go to the UCSC genome browser at Human hg19 chrX:15578261-15621068 UCSC Genome Browser v429. Look for the human gene he
Posted: Mon May 23, 2022 12:49 pm
Go to the UCSC genome browser at Human hg19
chrX:15578261-15621068 UCSC Genome Browser v429.
Look for the human gene hemoglobin beta (HBB).
1. What are the coordinates of the
gene? (1 mark)
2. Using the data from GTEx RNA-seq, identify the cells that
express it the most and the least (2 marks)
3. Which type of gene it this one?
(1mark)
4. How many exon it has? (1 mark)
5. What transcription factor binds
strongly around the promoter of the gene? (1 mark)
6. Does it have a CpG island at the promoter
(1mark).
7. The histone mark that marks active
enhancers and promoters is H3K27Ac. What tissue/cell shows a pick
of H3K27AC? What type of tissue/cell is that?
chrX:15578261-15621068 UCSC Genome Browser v429.
Look for the human gene hemoglobin beta (HBB).
1. What are the coordinates of the
gene? (1 mark)
2. Using the data from GTEx RNA-seq, identify the cells that
express it the most and the least (2 marks)
3. Which type of gene it this one?
(1mark)
4. How many exon it has? (1 mark)
5. What transcription factor binds
strongly around the promoter of the gene? (1 mark)
6. Does it have a CpG island at the promoter
(1mark).
7. The histone mark that marks active
enhancers and promoters is H3K27Ac. What tissue/cell shows a pick
of H3K27AC? What type of tissue/cell is that?