Propose a synthetic pathway to 1,3-dichlorobenzene, with benzene as the starting material. Give the appropriate reagent
Posted: Mon May 23, 2022 2:23 am
Propose a synthetic pathway to 1,3-dichlorobenzene, with benzene
as the starting material. Give the appropriate
reagent/solvent/catalyst for every step. The conversion
should be done in no more than FIVE steps. You can use any
substance. (example: 1. CH3MgBr, THF; 2. H3O+ shows a two-step
synthesis. You don't need to worry about
superscripts/subscripts. All common abbreviations used in the class
are accepted here. For instance, TsOH=p-toluenesulfonic acid;
NaOMe=sodium methoxide; NaOEt=sodium ethoxide)
as the starting material. Give the appropriate
reagent/solvent/catalyst for every step. The conversion
should be done in no more than FIVE steps. You can use any
substance. (example: 1. CH3MgBr, THF; 2. H3O+ shows a two-step
synthesis. You don't need to worry about
superscripts/subscripts. All common abbreviations used in the class
are accepted here. For instance, TsOH=p-toluenesulfonic acid;
NaOMe=sodium methoxide; NaOEt=sodium ethoxide)