Q2. Huntington's disease is a late onset autosomal dominant disorder. ~50% of Huntington heterozygotes show disease symp

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Q2 Huntington S Disease Is A Late Onset Autosomal Dominant Disorder 50 Of Huntington Heterozygotes Show Disease Symp 1 (434.72 KiB) Viewed 139 times

Q2. Huntington's disease is a late onset autosomal dominant disorder. ~50% of Huntington heterozygotes show disease symptoms by age 50. 100 90 80 1 70 60 Percentage affected 50 40 11 50 years 30 20 10 III 0 0 10 20 60 70 80 10 years 30 40 50 Age of onset (years) 1-2 is a heterozygote. If Il-1 is still healthy at 50, a. Use Bayesian analysis to calculate the probability that he carries the Huntington disease allele. Provide answers to 2 decimal places. Scenario A (II-1) carriers the disease allelle Scenario B (11-1) is not a carrier Prior Probability Cond. Probability Joint probability Posterior probability b. Calculate the chances of his daughter (III-1) inheriting the Huntington disease allele. There is no need here to consider the fact that she is unaffected. The probability that III-1 has inherited the Huntington disease allele (to three decimal places) =