2. Drawn below is the natural product ammosamide C. The ammosamide line of alkaloid natural products have shown to have
Posted: Sun May 22, 2022 4:49 pm
2. Drawn below is the natural product ammosamide C. The ammosamide line of alkaloid natural products have shown to have some interesting bioactivity against non-small cell lung cancer. NH2 H2N CI өсн, NH2 ammosamide C (a) In the space provided, name all the functional groups present in this structure there are technically 6 answers - CH, is not a functional group): (b) This molecule would appear to be anti-aromatic by Huckel's rule. However, this molecule is in fact aromatic. Briefly explain how Huckel's rule would predict this molecule to be anti- aromatic (c) As mentioned above, the molecule is indeed aromatic. Please provide a brief explanation as to why this molecule is an exception to Huckel's rule, specifically referencing either the molecule's planarity and/or the potential for multiple t systems.