3. It is known that Leber hereditary optic neuropathy (LHON) is an inherited form of blindness due to the missense mutat
Posted: Wed May 18, 2022 8:11 pm
3. It is known that Leber hereditary optic neuropathy (LHON) is
an inherited form of blindness due to the missense mutations of
mitochondrially encoded proteins of complexes I or III of the ETC.
Explain why disorder in the structure of these components of ETC
can impair electron transport and oxidative phosphorylation. For
the answer: a) draw the scheme of ETC and describe the structure of
its components; b) explain how the electrochemical gradient is
generated during the transport of the electrons;
c) explaine what the respiratory control of the ETC and P/O
ratio is.
an inherited form of blindness due to the missense mutations of
mitochondrially encoded proteins of complexes I or III of the ETC.
Explain why disorder in the structure of these components of ETC
can impair electron transport and oxidative phosphorylation. For
the answer: a) draw the scheme of ETC and describe the structure of
its components; b) explain how the electrochemical gradient is
generated during the transport of the electrons;
c) explaine what the respiratory control of the ETC and P/O
ratio is.