2. A Robinson Annulation is just a Michael Addition followed by an intramolecular Aldol Condensation. A variation of thi
Posted: Wed May 18, 2022 11:29 am
2. A Robinson Annulation is just a Michael Addition followed by an intramolecular Aldol Condensation. A variation of this reaction is a Michael Addition followed by and intramolecular Claisen Condensation. The first reaction below is a Robinson Annulation, with one compound missing. NaOH HO . Compound Compound w Compound X a. Provide the structure of Compound W needed to complete the reaction as shown. b. Circle the term that describes Compound W in this context. Michael Acceptor / Michael Donor Product Y has a carbonyl group, which compound does this come from? Circle one V/W The next reaction is an example of the Claisen variation. c. NaOET EtOH OET Compound V Compound Y Compound Z Unit 4 - Written Assignment Name: d. Propose a '6-Step' mechanism for the formation of the Compound Z including the key step shown below and give annotations explaining each step i.e. what is happening and why.