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The Robinson annulation is a combination of two carbonyl coupling reactions, the Michael reaction and the intramolecular aidol condensation The most common partners in the reaction are a nucleophilic donor (such as a cyclic ketone, a B-keto ester, an enamine, or a B-diketone) and an a,B-unsaturated ketone acceptor. The product is a substituted 2-cyclohexenane derivative, The above reaction between a enamine and an o, B-unsaturated ketone yields a product containing a 2-cyclohexenone ring. One of the steps of this reaction follows Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow-pushing Instructions nn - H-A А" OH SOH ) Next Emal structor Save and EX
The Robinson annulation is a combination of two carbonyl coupling reactions, the Michael reaction and the intramolecular aldol condensation The most common partners in the reaction are a nucleophilic donor (such as a cyclic ketone, a B-keto ester, an enamine, or a B-diketone) and an a,ß-unsaturated ketone acceptor. The product is a substituted 2-cyclohexenone derivative. The above reaction between a enamine and an a, B-unsaturated ketone yields a product containing a 2-cyclohexenone ring. One of the steps of this reaction follows. Draw curved arrows to show the movement of electrons in this step of the mechanism. Arrow.pushing Instructions OH OH <Previous Nexd Submit Answer Ratry Entire Group 9 more group attempts remaining Email Instructor Save and