a. For the reaction of 1-methoxy-4-methylbenzene with CH3C(O)Cl in the presence of AlCl3, describe the bonding and elect
Posted: Wed May 18, 2022 10:03 am
a. For the reaction of 1-methoxy-4-methylbenzene with
CH3C(O)Cl in the presence of AlCl3, describe
the bonding and electron distribution in 1-methoxy-4-methylbenzene,
formation and structure of the electrophile in the reaction, and
the most stable intermediate responsible for the end
product.
b. Use phenol as the substrate, propose a synthetic scheme to
produce 2-allyl-4-bromophenol (Mechanism not required).
c. Propose a synthesis of Compound
A starting from benzaldehyde and other necessary
reagents of your choice (Mechanism not required).
d. For the given 13C NMR chemical shifts of
the carbonyl carbons in the order of ketones > aldehydes >
carboxylic acids, provide an explanation.
CH3C(O)Cl in the presence of AlCl3, describe
the bonding and electron distribution in 1-methoxy-4-methylbenzene,
formation and structure of the electrophile in the reaction, and
the most stable intermediate responsible for the end
product.
b. Use phenol as the substrate, propose a synthetic scheme to
produce 2-allyl-4-bromophenol (Mechanism not required).
c. Propose a synthesis of Compound
A starting from benzaldehyde and other necessary
reagents of your choice (Mechanism not required).
d. For the given 13C NMR chemical shifts of
the carbonyl carbons in the order of ketones > aldehydes >
carboxylic acids, provide an explanation.