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5. (10) A cytosine is deaminated in a DNA molecule. Draw the consequences of this event and indicate whether this create
Posted: Tue May 17, 2022 3:56 pm
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- 5 10 A Cytosine Is Deaminated In A Dna Molecule Draw The Consequences Of This Event And Indicate Whether This Create 1 (35.56 KiB) Viewed 115 times
5. (10) A cytosine is deaminated in a DNA molecule. Draw the consequences of this event and indicate whether this creates a transition or transversion. What single bp changes could cytosine deamination produce in an Asp codon? Show codon changes to explain your response, and use terms silent, conservative and/or non-conservative. Now, consider what would happen if base excision repair (BER) were to occur prior to DNA replication. How would this change the outcome of the deamination? Briefly describe the five steps of BER needed for this deamination event. Explain how BER and mismatch repair work together to keep u low for SNPs vs. STR loci. What errors do they repair? What errors do they not repair?