Answer Happy

Histone tails project out from a nucleosome core. Certain amino acid residues on these tails may be modified, affecting the chromatin. Describe in detail the roles of histone acetylation and histone methylation. In your answer include information about: a) Which enzymes are responsible for these catalyzing these modifications b) Which amino acid residues can be modified c) Whether or not these modifications are reversible (and which enzymes may reverse them, if so) d) Which enzymes (or protein domains)"read" the modifications e) and what the resulting effect on DNA availability is for each (in general)