Base and nucleophile are both electron rich. You should be able to identify the electron rich site (basic or nucleophili
Posted: Tue May 17, 2022 8:56 am
Base and nucleophile are both electron rich. You should be able to identify the electron rich site (basic or nucleophilic site) in a compound. To be more accurate, you should be able to identify the electron pair (a lone pair or a shared pair) (shared electron pair means a bond) that can act as a base or a nucleophile. In the following compounds, identify (circle) the basic or nucleophilic electron pair, draw the curved electron flow arrow to lead the reaction, and draw the immediate product. [Additional information: Sometimes the stability of the intermediate/product will help you identify the more reactive electron pair in the reactant. For example, in the third reaction below, if the lone pair on the oxygen acted as a nucleophile it would produce an O-CI sigma bond with a positive charge on oxygen. That is not a stable intermediate and won't lead to a stable final product.) Draw the intermediates Is this a proton transfer or a nucleophilic attack + H-Br: OH Is this a proton transfer or a nucleophilic attack H-O: Is this a proton transfer or a nucleophilic attack ON Is this a proton transfer or a nucleophilic attack Fech, ci-FeCi CIH O: Is this a proton transfer or a nucleophilic attack 1